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About Zynomi

The AI-Native Clinical Data Company

We're building clinical data management as finished, human-approved work — a fleet of agents on the Zynomi Agent Fabric (ZAF), grounded in a clinical knowledge engine, working across the systems trials already run on.

Our Story

From automation pioneers to AI-native clinical data management

Zynomi's roots trace back to our early days as an automation company, leveraging open-source tools to eliminate mundane, repetitive tasks. When the GenAI wave arrived in 2022, it validated our core belief: automation is the future of work.

In 2023, our team—with deep experience in healthcare services and product engineering—took on a clinical trials engagement. What we discovered was a fragmented landscape: disconnected data systems, manual workflows, and infrastructure that wasn't ready for AI.

We saw the gap clearly. Clinical trials needed what other industries already had:modern data engineering, governed semantic layers, and AI-ready architectures. Our expertise in automation and data engineering wasn't just relevant—it was exactly what the industry was missing.

That insight became Zynomi. We now deliver an out-of-the-box data lakehouse for clinical trials, combining Data for AI (structured, governed datasets ready for machine learning) with AI for Data (intelligent automation for data engineering, quality, and compliance).

Built on the proven Frappe Framework and Marley Health, our platform delivers enterprise-grade reliability with healthcare-specific workflows—from data capture through governed analytics.

In 2026 we took the next step: rebuilding Zynomi ground-up as an AI-native platform. The Zynomi Agent Fabric (ZAF) puts a fleet of agents in every department, grounded in a clinical knowledge engine built from a clinical ontology and GraphRAG — with humans approving every result.

Our Journey

2021

Founded as automation company

2022

GenAI validates automation vision

2023

Clinical trials market entry

2024

Sublink launch & tech foundation

2025

Zynomi CDP V1.0 with Semantic Layer MVP Launch

2026

AI-native rebuild — Zynomi Agent Fabric (ZAF): agents on GraphRAG + clinical ontology

Our Vision

Clinical trials where AI agents do the data work — and humans approve every result.

Our Mission

Deliver clinical data management as finished, human-approved work — a fleet of agents on the Zynomi Agent Fabric (ZAF), grounded in a clinical knowledge engine, working across the systems trials already run on.

AI-NativeHuman-in-the-LoopOpen StandardsPatient-Centric

Modern Data Infrastructure

Standards-based architecture that eliminates technical debt

AI-Assisted Workflows

Reduce manual effort and minimize human error

Governed Semantic Layers

Real-time insights with regulatory readiness

Open APIs

Seamless integration with healthcare ecosystems

What Drives Us

Our Core Values

1

AI-Native

Agents do the data work — designed in from the start, not bolted on. Every workflow pairs an agent with the grounding it needs to do the job.

2

Human-in-the-Loop

Humans approve every result. Every agent output carries provenance and an accept/reject disposition.

3

Open Standards

We embrace CDISC, FHIR, MCP, and open-source technologies to ensure interoperability.

4

Patient-Centric

Faster trials mean faster access to life-saving treatments for patients.

Technology

Built on battle-tested foundations

Our platform combines Frappe Framework and Marley Health for clinical operations with a modern data stack for analytics and AI readiness.

Application Layer

FrappeERPNextMarley HealthNext.jsReact Native

Data & Analytics

PostgreSQLSupabasedbtRedisS3

Infrastructure

AWSFrappe CloudUpstash

AI & Observability

MCP ServerOpenTelemetryElementary

Ready to modernize your clinical trials?

See how Zynomi can accelerate your study execution and improve data quality.

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