About Zynomi
The AI-Native
Clinical Data Company
We're building clinical data management as finished, human-approved work — a fleet of agents on the Zynomi Agent Fabric (ZAF), grounded in a clinical knowledge engine, working across the systems trials already run on.
Our Story
From automation pioneers to AI-native clinical data management
Zynomi's roots trace back to our early days as an automation company, leveraging open-source tools to eliminate mundane, repetitive tasks. When the GenAI wave arrived in 2022, it validated our core belief: automation is the future of work.
In 2023, our team—with deep experience in healthcare services and product engineering—took on a clinical trials engagement. What we discovered was a fragmented landscape: disconnected data systems, manual workflows, and infrastructure that wasn't ready for AI.
We saw the gap clearly. Clinical trials needed what other industries already had:modern data engineering, governed semantic layers, and AI-ready architectures. Our expertise in automation and data engineering wasn't just relevant—it was exactly what the industry was missing.
That insight became Zynomi. We now deliver an out-of-the-box data lakehouse for clinical trials, combining Data for AI (structured, governed datasets ready for machine learning) with AI for Data (intelligent automation for data engineering, quality, and compliance).
Built on the proven Frappe Framework and Marley Health, our platform delivers enterprise-grade reliability with healthcare-specific workflows—from data capture through governed analytics.
In 2026 we took the next step: rebuilding Zynomi ground-up as an AI-native platform. The Zynomi Agent Fabric (ZAF) puts a fleet of agents in every department, grounded in a clinical knowledge engine built from a clinical ontology and GraphRAG — with humans approving every result.
Our Journey
2021
Founded as automation company
2022
GenAI validates automation vision
2023
Clinical trials market entry
2024
Sublink launch & tech foundation
2025
Zynomi CDP V1.0 with Semantic Layer MVP Launch
2026
AI-native rebuild — Zynomi Agent Fabric (ZAF): agents on GraphRAG + clinical ontology
Clinical trials where AI agents do the data work — and humans approve every result.
Deliver clinical data management as finished, human-approved work — a fleet of agents on the Zynomi Agent Fabric (ZAF), grounded in a clinical knowledge engine, working across the systems trials already run on.
Modern Data Infrastructure
Standards-based architecture that eliminates technical debt
AI-Assisted Workflows
Reduce manual effort and minimize human error
Governed Semantic Layers
Real-time insights with regulatory readiness
Open APIs
Seamless integration with healthcare ecosystems
What Drives Us
Our Core Values
AI-Native
Agents do the data work — designed in from the start, not bolted on. Every workflow pairs an agent with the grounding it needs to do the job.
Human-in-the-Loop
Humans approve every result. Every agent output carries provenance and an accept/reject disposition.
Open Standards
We embrace CDISC, FHIR, MCP, and open-source technologies to ensure interoperability.
Patient-Centric
Faster trials mean faster access to life-saving treatments for patients.
Technology
Built on battle-tested foundations
Our platform combines Frappe Framework and Marley Health for clinical operations with a modern data stack for analytics and AI readiness.
Application Layer
Data & Analytics
Infrastructure
AI & Observability
Ready to modernize your clinical trials?
See how Zynomi can accelerate your study execution and improve data quality.